Genotoxicity Studies

Genes are the most important material in the cell. All the cellular functions and morphology are controlled by gene expression. When gene damage happens, the function of cell will change, even increasing the risk of cancer. The purpose of genotoxicity studies is to evaluate whether the test article directly or indirectly causes genetic damage and identify the carcinogenicity of the test article by completely researching through bacterial, cell, and animal fields.

SuperLab is the first to establish the gene mutation test using the Hprt gene in Taiwan. The in vitro gene mutation test using the genes TK, Hprt, and Xprt have been conducted by the OECD since 1997, but OECD used only Hprt for gene mutation testing in 2015. Because we evaluate the effects of the test articles on genes through more objective and extensive testing, we established the gene mutation test using Hprt in 2016.

SuperLab’s genotoxicity laboratory has received the Good Laboratory Practice (GLP) accreditation from the Taiwan Accreditation Foundation (TAF) and Taiwan‵s Food and Drug Administration (FDA). We offer a comprehensive range of genotoxicity evaluations for food, chemistry, and medical device products. Our experienced experts, well-qualified staff, and accredited facility provide professional advice and efficiently perform the tests for your products.

1. Bacterial Reverse Mutation
2. In Vitro Mammalian Chromosome Aberration Test
3. Mammalian Erythrocyte Micronucleus Test
4. In Vitro Gene Mutation Test (Hprt gene)